Update on diagnosis and monitoring of cystic fibrosis-related diabetes mellitus (CFRD).
نویسندگان
چکیده
Cystic fibrosis (CF) is the most common recessive autosomal disease among Caucasian. Children with CF have benefitted from advances in medical and nutritional treatments, and this can be gleaned from the improvement in the survival of these patients. The increase in the survival rate brought with it the appearance of co-morbidities related to CF. Nowadays cystic fibrosis-related diabetes (CFRD) is considered the most common complication associated with CF. It can appear as early as infancy or adolescence, and its prevalence can be as high as 50% in adult patients. Because of its high prevalence, difficulties in early detection and the risks involved, in recent years several studies and consensuses have focused on this condition, adding information about the epidemiology, pathophysiology, prognosis and treatment of CFRD. The main aspects of these new concepts, as well as the current recommendations for its diagnosis and follow-up, will be presented in this study.
منابع مشابه
Update on cystic fibrosis-related diabetes.
PURPOSE OF REVIEW The aim is to provide a detailed review of recent publications on cystic fibrosis-related diabetes (CFRD) with a particular focus on the interplay between cystic fibrosis (CF) lung disease and diabetes. RECENT FINDINGS CFRD is a form of diabetes that is distinct from type 1 or type 2 diabetes. CFRD remains very common and increases in prevalence with increasing age so that o...
متن کاملClinical Care Guidelines for Cystic Fibrosis–Related Diabetes
C ystic fibrosis–related diabetes (CFRD) is the most common comorbidity in people with cystic fibrosis (CF), occurring in 20% of adolescents and 40–50% of adults (1). While it shares features of type 1 and type 2 diabetes, CFRD is a distinct clinical entity. It is primarily caused by insulin insufficiency, although fluctuating levels of insulin resistance related to acute and chronic illness al...
متن کاملClinical Care Guidelines for Cystic Fibrosis–Related Diabetes A position statement of the American Diabetes Association and a clinical practice guideline of the Cystic Fibrosis Foundation, endorsed by the Pediatric Endocrine Society
C ystic fibrosis–related diabetes (CFRD) is the most common comorbidity in people with cystic fibrosis (CF), occurring in 20% of adolescents and 40–50% of adults (1). While it shares features of type 1 and type 2 diabetes, CFRD is a distinct clinical entity. It is primarily caused by insulin insufficiency, although fluctuating levels of insulin resistance related to acute and chronic illness al...
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BALTIMORE – Cystic fibrosis–related diabetes differs from type 1 and 2 diabetes and requires different management. “Screening early and knowing which patients are at risk is really important,” Amanda Leonard said at a meeting on pediatric nutrition sponsored by Johns Hopkins University. Pulmonary function begins to decline several years before diagnosis of cystic fibrosis– related diabetes (CFR...
متن کاملEpidemiology, Pathophysiology, and Prognostic Implications of Cystic Fibrosis–Related Diabetes
C ystic fibrosis–related diabetes (CFRD) is the most common comorbidity in subjects with cystic fibrosis (CF). A consensus conference on CFRD was cosponsored by the Cystic Fibrosis Foundation (CFF), the American Diabetes Association (ADA), and the Pediatric Endocrine Society (PES) in September 2009. The committee’s evidencebased recommendations for clinical management of CFRD are published in t...
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ورودعنوان ژورنال:
- Arquivos brasileiros de endocrinologia e metabologia
دوره 55 8 شماره
صفحات -
تاریخ انتشار 2011